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Jan 9

Red Blood Cell Segmentation with Overlapping Cell Separation and Classification on Imbalanced Dataset

Automated red blood cell (RBC) classification on blood smear images helps hematologists to analyze RBC lab results in a reduced time and cost. However, overlapping cells can cause incorrect predicted results, and so they have to be separated into multiple single RBCs before classifying. To classify multiple classes with deep learning, imbalance problems are common in medical imaging because normal samples are always higher than rare disease samples. This paper presents a new method to segment and classify RBCs from blood smear images, specifically to tackle cell overlapping and data imbalance problems. Focusing on overlapping cell separation, our segmentation process first estimates ellipses to represent RBCs. The method detects the concave points and then finds the ellipses using directed ellipse fitting. The accuracy from 20 blood smear images was 0.889. Classification requires balanced training datasets. However, some RBC types are rare. The imbalance ratio of this dataset was 34.538 for 12 RBC classes from 20,875 individual RBC samples. The use of machine learning for RBC classification with an imbalanced dataset is hence more challenging than many other applications. We analyzed techniques to deal with this problem. The best accuracy and F1-score were 0.921 and 0.8679, respectively, using EfficientNet-B1 with augmentation. Experimental results showed that the weight balancing technique with augmentation had the potential to deal with imbalance problems by improving the F1-score on minority classes, while data augmentation significantly improved the overall classification performance.

  • 5 authors
·
Dec 2, 2020

TAT: Task-Adaptive Transformer for All-in-One Medical Image Restoration

Medical image restoration (MedIR) aims to recover high-quality medical images from their low-quality counterparts. Recent advancements in MedIR have focused on All-in-One models capable of simultaneously addressing multiple different MedIR tasks. However, due to significant differences in both modality and degradation types, using a shared model for these diverse tasks requires careful consideration of two critical inter-task relationships: task interference, which occurs when conflicting gradient update directions arise across tasks on the same parameter, and task imbalance, which refers to uneven optimization caused by varying learning difficulties inherent to each task. To address these challenges, we propose a task-adaptive Transformer (TAT), a novel framework that dynamically adapts to different tasks through two key innovations. First, a task-adaptive weight generation strategy is introduced to mitigate task interference by generating task-specific weight parameters for each task, thereby eliminating potential gradient conflicts on shared weight parameters. Second, a task-adaptive loss balancing strategy is introduced to dynamically adjust loss weights based on task-specific learning difficulties, preventing task domination or undertraining. Extensive experiments demonstrate that our proposed TAT achieves state-of-the-art performance in three MedIR tasks--PET synthesis, CT denoising, and MRI super-resolution--both in task-specific and All-in-One settings. Code is available at https://github.com/Yaziwel/TAT.

  • 6 authors
·
Dec 16, 2025 1

YOLOv11-RGBT: Towards a Comprehensive Single-Stage Multispectral Object Detection Framework

Multispectral object detection, which integrates information from multiple bands, can enhance detection accuracy and environmental adaptability, holding great application potential across various fields. Although existing methods have made progress in cross-modal interaction, low-light conditions, and model lightweight, there are still challenges like the lack of a unified single-stage framework, difficulty in balancing performance and fusion strategy, and unreasonable modality weight allocation. To address these, based on the YOLOv11 framework, we present YOLOv11-RGBT, a new comprehensive multimodal object detection framework. We designed six multispectral fusion modes and successfully applied them to models from YOLOv3 to YOLOv12 and RT-DETR. After reevaluating the importance of the two modalities, we proposed a P3 mid-fusion strategy and multispectral controllable fine-tuning (MCF) strategy for multispectral models. These improvements optimize feature fusion, reduce redundancy and mismatches, and boost overall model performance. Experiments show our framework excels on three major open-source multispectral object detection datasets, like LLVIP and FLIR. Particularly, the multispectral controllable fine-tuning strategy significantly enhanced model adaptability and robustness. On the FLIR dataset, it consistently improved YOLOv11 models' mAP by 3.41%-5.65%, reaching a maximum of 47.61%, verifying the framework and strategies' effectiveness. The code is available at: https://github.com/wandahangFY/YOLOv11-RGBT.

  • 9 authors
·
Jun 17, 2025