Morpholine rings are common in drug molecules and natural products. There are many interesting methodologies for the construction of morpholine rings. Research groups have reported the conversion of furan derivatives to morpholines, as shown in the figure below. It is known that the product's 1H NMR spectrum contains 7 aromatic hydrogens.

<MultiModal>![OC(C1=CC=C(C(F)(F)F)C=C1)C2=CC=CO2 and NC1=CC(Cl)=CC=C1O react under the conditions of $TsOH, 80\degree C$](/media/uploads/e4411bf5-ec00-4b08-8766-00331086fbdc.png)</MultiModal>

Considering the product formation process, select the correct product structure.
吗啉环在药物分子和天然产物中都比较常见。针对吗啉环的构筑也有许多有趣的方法学。有课题组报道了呋喃衍生物转化为吗啉的反应，如下图所示。已知产物的核磁氢谱中有7个芳基氢。

<MultiModal>![OC(C1=CC=C(C(F)(F)F)C=C1)C2=CC=CO2和NC1=CC(Cl)=CC=C1O在$TsOH, 80\degree C$的条件下发生反应](/media/uploads/e4411bf5-ec00-4b08-8766-00331086fbdc.png)</MultiModal>

考虑产物生成的过程，选出正确的产物结构。
All other options are incorrect
<MultiModal>![O=C1[C@@H](C2=CC=C(C(F)(F)F)C=C2)[C@@H](NC3=C(O4)C=CC(Cl)=C3)[C@@H]4C1](/media/uploads/591639b6-cfc0-47fa-9c3a-f758502d9762.png)</MultiModal>
<MultiModal>![ClC1=CC=C(O[C@]2([C@@H](N3)C4=CC=C(C(F)(F)F)C=C4)C=CCO2)C3=C1](/media/uploads/8c0d254f-d513-4e50-8431-bedefa78cbd2.png)</MultiModal>
<MultiModal>![ClC1=CC=C(O[C@]2([C@@H](N3)C4=CC=C(C(F)(F)F)C=C4)CC2C=O)C3=C1](/media/uploads/7d9fb7ae-f81b-4999-9f62-30c2d69ec35e.png)</MultiModal>
<MultiModal>![ClC1=CC=C2C(N(C=CC3)C3=C(O2)C4=CC=C(C(F)(F)F)C=C4)=C1](/media/uploads/caf8cec1-e8a1-47da-a474-0f81cd373232.png)</MultiModal>
其他选项均不正确
<MultiModal>![O=C1[C@@H](C2=CC=C(C(F)(F)F)C=C2)[C@@H](NC3=C(O4)C=CC(Cl)=C3)[C@@H]4C1](/media/uploads/591639b6-cfc0-47fa-9c3a-f758502d9762.png)</MultiModal>
<MultiModal>![ClC1=CC=C(O[C@]2([C@@H](N3)C4=CC=C(C(F)(F)F)C=C4)C=CCO2)C3=C1](/media/uploads/8c0d254f-d513-4e50-8431-bedefa78cbd2.png)</MultiModal>
<MultiModal>![ClC1=CC=C(O[C@]2([C@@H](N3)C4=CC=C(C(F)(F)F)C=C4)CC2C=O)C3=C1](/media/uploads/7d9fb7ae-f81b-4999-9f62-30c2d69ec35e.png)</MultiModal>
<MultiModal>![ClC1=CC=C2C(N(C=CC3)C3=C(O2)C4=CC=C(C(F)(F)F)C=C4)=C1](/media/uploads/caf8cec1-e8a1-47da-a474-0f81cd373232.png)</MultiModal>
Only seven aryl hydrogens in the product suggest that the furan ring should have undergone ring-opening.

<Checkpoint>[Only seven aryl hydrogens in the product suggest that the furan ring should have undergone ring-opening.](1)</Checkpoint>

Dehydration of hydroxyfuran under acidic conditions yields the carbenium ion intermediate 1FC(C(C=C1)=CC=C1/C=C2[O+]=CC=C/2)(F)F,

<Checkpoint>[Dehydration of hydroxyfuran under acidic conditions](1)</Checkpoint>

<Checkpoint>[Carbenium ion intermediate 1 is FC(C(C=C1)=CC=C1/C=C2[O+]=CC=C/2)(F)F](1)</Checkpoint>

Subsequently, carbenium ion intermediate 1 undergoes ring-opening via aniline attack to give the intermediate OC(/C=C\C=N\C1=C(O)C=CC(Cl)=C1)=C/C2=CC=C(C(F)(F)F)C=C2.

<Checkpoint>[Carbenium ion intermediate 1 undergoes ring-opening via aniline attack to give ring-opened intermediate 2](1)</Checkpoint>

<Checkpoint>[Ring-opened intermediate 2 is OC(/C=C\C=N\C1=C(O)C=CC(Cl)=C1)=C/C2=CC=C(C(F)(F)F)C=C2](1)</Checkpoint>

Ring-opened intermediate 2 can undergo a Nazarov cyclization reaction to give O=C1[C@@H](C2=CC=C(C(F)(F)F)C=C2)[C@@H](NC3=C(O)C=CC(Cl)=C3)C=C1

<Checkpoint>[Ring-opened intermediate 2 can undergo a Nazarov cyclization reaction to give cyclized intermediate 3](1)</Checkpoint>

<Checkpoint>[Cyclized intermediate 3 is O=C1[C@@H](C2=CC=C(C(F)(F)F)C=C2)[C@@H](NC3=C(O)C=CC(Cl)=C3)C=C1](1)</Checkpoint>

Cyclized intermediate 3 can undergo an intramolecular Michael addition to give the product: O=C1[C@@H](C2=CC=C(C(F)(F)F)C=C2)[C@@H](NC3=C(O4)C=CC(Cl)=C3)[C@@H]4C1.

<Checkpoint>[Cyclized intermediate 3 can undergo an intramolecular Michael addition to give the product](1)</Checkpoint>

<Checkpoint>[The product is O=C1[C@@H](C2=CC=C(C(F)(F)F)C=C2)[C@@H](NC3=C(O4)C=CC(Cl)=C3)[C@@H]4C1](1)</Checkpoint>
Therefore, B is correct.

<MultiModal>![Carbenium ion intermediate 1: FC(C(C=C1)=CC=C1/C=C2[O+]=CC=C/2)(F)F
Ring-opened intermediate 2: OC(/C=C\C=N\C1=C(O)C=CC(Cl)=C1)=C/C2=CC=C(C(F)(F)F)C=C2
Cyclized intermediate 3: O=C1[C@@H](C2=CC=C(C(F)(F)F)C=C2)[C@@H](NC3=C(O)C=CC(Cl)=C3)C=C1
Product: O=C1[C@@H](C2=CC=C(C(F)(F)F)C=C2)[C@@H](NC3=C(O4)C=CC(Cl)=C3)[C@@H]4C1](/media/uploads/d3be1b03-8bb6-41f8-a2dd-4edb301f9d3b.png)</MultiModal>
产物中只有七个芳基氢，暗示着呋喃环应该发生了开环。

<Checkpoint>[产物中只有七个芳基氢，暗示着呋喃环应该发生了开环。](1)</Checkpoint>

羟基呋喃在酸性条件下脱水得到正离子中间体1FC(C(C=C1)=CC=C1/C=C2[O+]=CC=C/2)(F)F，

<Checkpoint>[羟基呋喃在酸性条件下脱水](1)</Checkpoint>

<Checkpoint>[正离子中间体1为FC(C(C=C1)=CC=C1/C=C2[O+]=CC=C/2)(F)F](1)</Checkpoint>

此后正离子中间体1受到苯胺进攻开环得到OC(/C=C\C=N\C1=C(O)C=CC(Cl)=C1)=C/C2=CC=C(C(F)(F)F)C=C2中间体。

<Checkpoint>[正离子中间体1受到苯胺进攻开环得到开环中间体2](1)</Checkpoint>

<Checkpoint>[开环中间体2为OC(/C=C\C=N\C1=C(O)C=CC(Cl)=C1)=C/C2=CC=C(C(F)(F)F)C=C2](1)</Checkpoint>

开环中间体2可以发生Nazarov环化反应得到O=C1[C@@H](C2=CC=C(C(F)(F)F)C=C2)[C@@H](NC3=C(O)C=CC(Cl)=C3)C=C1

<Checkpoint>[开环中间体2可以发生Nazarov环化反应得到环化中间体3](1)</Checkpoint>

<Checkpoint>[环化中间体3为O=C1[C@@H](C2=CC=C(C(F)(F)F)C=C2)[C@@H](NC3=C(O)C=CC(Cl)=C3)C=C1](1)</Checkpoint>

环化中间体3可以发生一次分子内的Michael加成得到产物：O=C1[C@@H](C2=CC=C(C(F)(F)F)C=C2)[C@@H](NC3=C(O4)C=CC(Cl)=C3)[C@@H]4C1。

<Checkpoint>[环化中间体3可以发生一次分子内的Michael加成得到产物](1)</Checkpoint>

<Checkpoint>[产物为O=C1[C@@H](C2=CC=C(C(F)(F)F)C=C2)[C@@H](NC3=C(O4)C=CC(Cl)=C3)[C@@H]4C1](1)</Checkpoint>
因此B是正确的。

<MultiModal>![正离子中间体1：FC(C(C=C1)=CC=C1/C=C2[O+]=CC=C/2)(F)F
开环中间体2：OC(/C=C\C=N\C1=C(O)C=CC(Cl)=C1)=C/C2=CC=C(C(F)(F)F)C=C2
环化中间体3：O=C1[C@@H](C2=CC=C(C(F)(F)F)C=C2)[C@@H](NC3=C(O)C=CC(Cl)=C3)C=C1
产物：O=C1[C@@H](C2=CC=C(C(F)(F)F)C=C2)[C@@H](NC3=C(O4)C=CC(Cl)=C3)[C@@H]4C1](/media/uploads/d3be1b03-8bb6-41f8-a2dd-4edb301f9d3b.png)</MultiModal>