Interventions that Address Structural Racism to Reduce Kidney Health Disparities Research Coordinating Center
NIH
DUKE UNIVERSITY
PROJECT ABSTRACT Recognizing the significant impact of structural racism on kidney health in minority populations, the NIH is creating a new Consortium focused on Interventions that Address Structural Racism to Reduce Kidney Health Disparities. The Consortium will bring together research teams from six Intervention Sites to conduct community-engaged intervention studies to address structural racism and reduce disparities across the spectrum of kidney health and disease. We propose to serve as the Research Coordinating Center (RCC) for the Consortium. The Duke RCC will leverage extensive institutional resources and expertise at Duke University to provide administrative leadership and research coordination to ensure seamless operations of the Consortium and successful conduct of Consortium studies; support rigorous data collection, data management, and data analysis for Consortium studies; and foster research collaboration, capacity-building, and workforce diversification in kidney health equity research. Three closely integrated cores will lead the core activities of the RCC. The Administrative and Coordination Core will provide administrative, operational, and logistical support to the Consortium, including coordinating meetings, developing a secure web-based communications and collaboration platform, supporting program management and regulatory submissions, administering an opportunity pool for ancillary studies, and continually evaluating and enhancing Consortium operations. The Data Management and Analysis Core will contribute to the final design of Consortium studies, provide data monitoring for multi-site Consortium studies, and support statistical analysis for multi-site Consortium studies and pooled analyses of common data elements across the Consortium. The Collaboration and Community Engagement Core will foster a vibrant and collaborative research community within and beyond the Consortium by facilitating discussion at Consortium meetings and workshops, supporting dissemination of Consortium results to the broader research and lay communities, integrating selected NIH career development awardees in relevant Consortium activities, and exposing early-career trainees from underrepresented groups to kidney- focused structural racism scholarly work in order to successfully implement health equity research and interventions. Together, the multidisciplinary RCC team will ensure the successful completion of multiple intervention trials targeting disparities in kidney health and build a diverse and sustainable community of researchers and community partners focused on improving kidney health in marginalized populations. PROJECT NARRATIVE Structural racism is an important contributor to disparities in kidney disease. The proposed research coordinating center will support a research network and multiple clinical trials focused on addressing structural racism to reduce disparities in kidney health and disease.
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