Anatomical and functional cardiac CT imaging in patients with chest pain syndromes - The DYNAMITE trial
Novo Nordisk Foundation
Copenhagen University Hospital
Individuals suffering from chest pain may have serious cardiac vascular disease that may result in debilitating symptoms and reduced life-time expectancy. Current examination primarily involves invasive investigation of the heart – so-called coronary angiography – which carries a risk of procedural complications. Several studies have suggested that coronary angiography might be replaced by the safer and non-invasive cardiac CT angiography (CCTA). Technological developments have suggested that with advanced cardiac CT imaging the functional importance of disease could be determined and used to guide treatment. The aim of this study is in a large group of patients suffering from chest pain to assess the potential benefit of advanced cardiac CT imaging in terms of symptom relief and improved life-time expectancy, compared to a conventional evaluation strategy. If the study is positive, implementation of this new approach will improve the life of many patients with heart disease.
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