A Trial of Negative Ion Generation Versus Light-Emitting Diode Phototherapy for Seasonal Affective Disorder (SAD)
Clinical Associates Research, Maryland
Yale University

      This is a randomized, controlled clinical trial of inactivated negative ion generation or
      light-emitting photodiode therapy for Seasonal Affective Disorder (SAD, winter depression),
      for subjects with a DSM IV diagnosis of Major Depression, with Seasonal Pattern, Winter type,
      to examine efficacy of treatments for this condition. The trial has a 1 week baseline phase
      and a 4 week treatment phase.
    
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