Renal Graft Function After Treatment With Erythropoietin (EPO)
Hoffmann-La Roche
CHU LIMOGES

      Background : Numerous studies have outlined the cellular pleiotropic effects of
      erythropoietin (EPO) and their role in the prevention of ischemic-reperfusion lesion such as
      after acute ischemic injury of the brain or the heart. However, most of these studies were
      carried out in animal models and no definitive proof exists today to demonstrate that EPO has
      similar beneficial effects in human pathology.

      Purpose : The aim of the study is to demonstrate that in humans, EPO can protect against
      ischemic-reperfusion lesions in a model of ischemia i.e. kidney transplantation.
    
Drug