Structured Treatment of Osteoarthritis of the Knee With or Without Total Knee Replacement
Medical Specialist Heinrich Kopp's Grant
Center for Sensory-Motor Interaction (SMI), Department of Health Sciences and Technology, Aalborg University

      The purpose of this study is to test whether surgical insertion of total knee replacement
      provides further improvement in quality of life, pain and function in addition to an
      algorithm for systematic non-surgical treatment consisting of corrective insoles,
      neuromuscular training, weight loss, patient education and pharmacological treatment with
      paracetamol, NSAIDs and Pantoprazol in patients with knee OA, collectively called the
      MEDIC-treatment(Medicine Exercise Diet Insoles Cognitive).

      The H1-hypothesis is that surgery with insertion of TKR in addition to the MEDIC-treatment
      results in a greater increase in quality of life and functional capacity and greater
      reduction in pain than the MEDIC- treatment alone at the primary endpoint, which is follow-up
      12months after the start of the treatment.

      See statistical analysis plan available under "Links" for further description of the study.
    
Behavioral