Effect of a 10,000 EU Dose of Endotoxin in Allergic and Mildly Asthmatic Adults
National Heart, Lung, and Blood Institute (NHLBI)
University of North Carolina at Chapel Hill, Dept of Pediatrics / Center for Environmental Medicine, Asthma and Lung Biology

      The purposes of this pilot safety study are to identify a dose of inhaled Clinical Center
      Reference Endotoxin (CCRE) that is well tolerated by allergic subjects that induces
      measurable increases in neutrophil content of induced sputum that can be employed to screen
      large populations for susceptibility to the inflammatory effect of inhaled endotoxin.
    
Biological