AZD2171 and Temsirolimus in Patients With Advanced Gynecological Malignancies
Massachusetts General Hospital
Dana-Farber Cancer Institute

      The purpose of this research study is to determine the safety of the combination of the two
      drugs cediranib and temsirolimus and the highest doses of these two drugs that can be given
      in combination to people safely. Cediranib is a drug that may stop blood supply to the tumor
      and therefore help keep cancer cells from growing. Temsirolimus is a drug that may stop
      cancer cells from growing. These drugs have been used in other research studies in ovarian
      and kidney cancer and these studies suggest that these drugs may help to keep cancer from
      growing in this research study.
    
Drug